Single drug or polypharmacy?
نویسندگان
چکیده
منابع مشابه
Polypharmacy versus Drug Combinations
Drug combinations have been known to be used either for increasing effcctivity or for decreasing side-efFects. It is only when multiple drugs are prescribed without adequate scientific evidence in their favour then such practices need careful scrutiny. Multiple drug use in psychiatry has recently gained currency and so require thoughtful consideration. The term polypharmacy is generally used to...
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Adverse drug reactions (ADRs) induced from high-order drug-drug interactions (DDIs) due to polypharmacy represent a significant public health problem. In this paper, we formally formulate the to-avoid and safe (with respect to ADRs) drug recommendation problems when multiple drugs have been taken simultaneously. We develop a joint model with a recommendation component and an ADR label predictio...
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The elderly are at risk for polypharmacy, which is associated with significant consequences such as adverse effects, medication nonadherence, drug-drug and drug-disease interactions, and increased risk of geriatric syndromes. Providers should evaluate all existing medications at each patient visit for appropriateness and weigh the risks and benefits of starting new medications to minimize polyp...
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To reveal any potential bias in this publication, and in accordance with Accreditation Council for Continuing Medical Education guidelines, Dr. Hocum (author) reports he is a stockholder and clinical pharmacist at Genelex Corporation. Dr. E. Black (author), Dr. K. Black (author), Dr. Beatty (peer reviewer), Dr. Wise (editor), Ms. Coplin (executive editor), and Ms. Hamlin (managing editor) repor...
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Background: Drug-drug interactions (DDI) are actually quite commonplace and are responsible for considerable patient morbidity and mortality. The two major varieties of DDI are pharmacodynamic and pharmacokinetic interactions (cytochrome P450 system). Conditions such as bipolar disorder (with many psychiatric and somatic comorbidities) are complex symptom clusters and bipolar patients may need ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1980
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.280.6216.790-d